Two people were killed Thursday after a plane crash in Giles County. The single-engine Beechcraft 35 plane reportedly took off from Knoxville Thursday morning at approximately 10:50 eastern time. The plane crash is believed to have happened at approximately 11:15 central time on Diana Ridge Road. The Federal Aviation Administration said contact was lost with the plane. The FAA and National Transportation Safety Board will investigate the crash with the NTSB taking the lead. At the time of this report no names have been released.